Giant Rats and Dedicated Volunteers Transform TB Detection in Tanzania

A “hero-rat” from Apopo.

In Tanzania, where tuberculosis remains a critical health challenge, two organizations are making remarkable strides in detection and treatment. Apopo, a Belgian-founded charity, has pioneered the use of African giant pouched rats to screen TB samples, while Mkuta provides vital community health support and treatment access.

Apopo’s innovative program has analyzed over 900,000 samples since 2007, identifying more than 30,000 TB cases that conventional testing missed. The rats, which can grow up to 90cm long, are trained from four weeks old to detect Mycobacterium tuberculosis through their acute sense of smell. Their accuracy is impressive – research shows they correctly identify TB in at least 82% of cases compared to standard clinical tests.

An Apopa giant rat sniffing TB samples.

The program’s efficiency and cost-effectiveness are striking. A rat can screen hundreds of samples within minutes, costing just 90 pence per sample compared to up to £12 for molecular tests. The success has led to expansion plans, with a new laboratory opening in Moshi and potential programs in Sierra Leone and Angola.

“One untreated person can infect 10-15 people, multiply that by 24,000 people correctly treated, who had been missed through regular tests. These were not just samples, these were lives saved,” said Dr. Joseph Soka, manager at Apopo’s laboratory, in an interview with The Guardian.

Working alongside Apopo, Mkuta’s volunteers play a crucial role in community outreach and patient support. They identify potential TB cases, facilitate treatment access, and help combat stigma. The combined efforts of both organizations, along with other government and NGO programs, have contributed to a 40% reduction in TB incidence in Tanzania since 2015.


Read the fascinating article by Peter Muiruri from December 18, 2024 in The Guardian: Cheap, smart and efficient: how giant rats are transforming the fight against TB

Watch this video to learn how these herorats detect TB:

See the life saving HeroRATs in action at our lab in Maputo.

Watch this video to learn more about Mkuta:

Through the Challenge Facility for Civil Society Round 10 Grant, MKUTA engaged TB patients in Temeke and Kigoma-Ujiji Municipals to submit service and social barriers preventing them from accessing TB services, with a view of removing these barriers for the improvement of TB services and the reduction of stigma and discrimination of TB patients. This is a first-hand account from Temeke Municipal.

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